Donepezil ikoreshwa mu kuvura urujijo rujyanye n'indwara ya Alzheimer.
izina RY'IGICURUZWA | Donepezil Hydrochloride |
Izina ryimiti | 1h-inden-1-umwe, 2,3-dihydro-5,6-dimethoxy-2 - ((1- (phenylmethyl) -4-piperidinyl) njye |
Irindi zina | Donepezil hcl; Donezepilhydrochloride; DonepezilHydrochloride (200mg); 2 - ((1-Benzylpiperidin-4-yl) Methyl) -5,6-diMethoxy-2,3-dihydro-1H-inden-1-onehydrochloride; -5,6-diMetChemicalbookhoxy-2 - [[[1- (phenylMethyl) -4-piperidinyl] Methyl] -; 2- (1- ); DonepezilHydrochlorideForMⅠ |
Umubare CAS | 120011-70-3 |
Inzira ya molekulari | C24H30ClNO3 |
Uburemere bwa formula | 415.95 |
Kugaragara | Umweru kugeza kuri-cyera kristaline ikomeye |
Suzuma | 98.0% min |
Ingingo yo gushonga | 220-222 ° C. |
Ingingo | 527.9 C Kuri 760 MmHg |
Amapaki | 20kg / umufuka / ingoma, 25kg / umufuka / ingoma, cyangwa nkuko ubisabwa |
Ububiko | Bika kontineri ifunze cyane ahantu humye & akonje.Ntugaragaze urumuri rw'izuba. |
COA & MSDS | Birashoboka |
Gusaba | Kubushakashatsi |
IKIZAMINI CYIZA | UMWIHARIKO | IGISUBIZO |
Kugaragara | Kureka ifu yera kugeza yera | Bikubiyemo |
Gukemura | Kubora kubusa muri chloroform, gushonga mumazi na acide Acetike, gushonga gake muri Acetonitrile na Ethanol, bidashonga muri Ethylacetoacetate na n-hexane. | Bikubiyemo |
Kumenyekanisha | (1) Kubijyanye no kwinjiza IR, Guhuza nibikorwa bisanzwe. | Bikubiyemo |
(2) Igihe cyo kugumana impinga nkuru yicyitegererezo igomba guhuza nigihe cyakazi. | Bikubiyemo | |
(3) Ikizamini cya chloride.Igisubizo ku kizamini cya Chloride. | Bikubiyemo | |
Amazi | ≤0.4% | 0.31% |
Ibisigisigi byo gutwikwa | ≤0.1% | 0,02% |
Ibintu bifitanye isano | Desbenzyl donepezla≤0.15% Donepezil pyridine analogb≤0.15% Donepezilzilbenzyl bromidec≤0.15% Dehydrodeoxy donepezild≤0.15% Deoxy donepezile≤0.15% Ikintu cyose kidahwitse cyanduye0.0% Igiteranyo cya .5 0.5% | Ntibimenyekana Ntibimenyekana 0,02% Ntibimenyekana Ntibimenyekana 0,05% 0.18% |
Icyuma kiremereye | ≤20ppm | ≤20ppm |
Ibisigisigi bisigaye | Methanol≤0.3%Ethanol≤0.5%Ethyl acetate≤ 0.5% Toluene≤0.089% Acide acike≤0.5% | Ntibimenyekana Ntibimenyekana Ntibimenyekana Ntibimenyekana Ntibimenyekana |
Suzuma | Ku cyuma cyumye, C.24H29NO3· HCl igomba kuba 98.0% kugeza 102.0%. | 99.52% |
Donepezil Hydrochloride ni umunyu wa hydrochloride yumunyu wa piperidine ukomoka hamwe nibikorwa byongera neurocognitive.Donepezil ihagarika byimazeyo acetylcholinesterase, bityo igahagarika hydrolysis ya neurotransmitter acetylcholine, bityo, ikongera ibikorwa byayo.
Nigute nafata Hydrochloride ya Donepezil?
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Kuyobora igihe
≤100kg: mu minsi itatu y'akazi nyuma yo kwishyura.
>100kg: icyumweru kimwe
Icyitegererezo
Birashoboka.
Amapaki
20kg / umufuka / ingoma, 25kg / igikapu / ingoma
cyangwa nkuko ubisabwa.
Ububiko
Bika kontineri ifunze cyane ahantu humye & akonje.
Ntugaragaze urumuri rw'izuba.