API Pitavastatin Kalisiyumu CAS 147526-32-7

Ibisobanuro bigufi:

Pitavastatin ikoreshwa hamwe nimirire iboneye kugirango ifashe kugabanya cholesterol "mbi" hamwe namavuta (nka LDL, triglyceride) no kuzamura cholesterol "nziza" (HDL) mumaraso.

Twandikire: Erica Zheng

Email: erica@zhuoerchem.com

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Ibicuruzwa birambuye

Ibicuruzwa

Ibisobanuro

Pitavastatine ikoreshwa hamwe nimirire iboneye kugirango ifashe kugabanya cholesterol "mbi" hamwe n amavuta (nka LDL, triglyceride) no kuzamura cholesterol "nziza" (HDL) mumaraso.

Ibisobanuro:

izina RY'IGICURUZWA	Kalisiyumu ya Pitavastatin
Izina ryimiti	Kalisiyumu; (E, 3R, 5S) -7- [2-cyclopropyl-4-
Irindi zina	PitavasttinCalcium; PitavastatinCalcium / NK-104; (+) - Monocalciunbis {(3r, 5s, 6e) -7- [2-cyclopropyl-4- }; PitavastatincalciuM (Livalo); Kalisiyumu (3R, 5S, E) -7- , 5S, 6E) -7- [2-cyclopropyl-4- (4-fluorophenil)
Umubare CAS	147526-32-7
Inzira ya molekulari	C25H26CaFNO4
Uburemere bwa formula	463.56
Kugaragara	Birakomeye
Suzuma	98.0% min
Amapaki	20kg / umufuka / ingoma, 25kg / umufuka / ingoma, cyangwa nkuko ubisabwa
Ububiko	Bika kontineri ifunze cyane ahantu humye & akonje.Ntugaragaze urumuri rw'izuba.
COA & MSDS	Birashoboka

Ikoreshwa

Kalisiyumu ya Pitavastatin ni inzitizi irwanya enzyme HMGCR (HMG-CoA reductase) itera kugabanuka kwa LDL ya cholesterol.Ubundi bushakashatsi bwerekana ko pitavastatine ishobora guhagarika umusaruro wa ogisijeni mu ngirabuzimafatizo ya endothelia mu kubuza okiside ya NADPH.Byongeye kandi, pitavastatin igabanya imvugo ya eNOS mRNA mugihe yongerera OYA igisubizo giterwa na acetylcholine na calcium ionophore, A23187.Byongeye kandi, pitavastatin ibuza kugenzura-imiyoboro ya calcium ikoreshwa na potasiyumu ya calcium igabanya urugero rwa cholesterol mu ngirabuzimafatizo.